کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1314541 | 975973 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
α-Fluoroalkylation of carbonyl compounds mediated by a highly reactive alkyl-rhodium complex
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی معدنی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: α-Fluoroalkylation of carbonyl compounds mediated by a highly reactive alkyl-rhodium complex α-Fluoroalkylation of carbonyl compounds mediated by a highly reactive alkyl-rhodium complex](/preview/png/1314541.png)
چکیده انگلیسی
Treatment of silyl enol ethers of various carbonyl compounds with Et2Zn and fluoroalkyl halides (Rf–X) in the presence of RhCl(PPh3)3 in DME gave the corresponding α-Rf carbonyl compounds. A highly reactive alkyl-rhodium complex which was derived from RhCl(PPh3)3 and Et2Zn must be crucial in this reaction by accelerating the reaction rate and improving the yields dramatically. This reaction overcomes difficulties on the synthesis of α-Rf carbonyl compounds due to inverse polarization of Rf–X.
The treatment of silyl enol ethers with fluoroalkyl halides (Rf–X) and Et2Zn in the presence of RhCl(PPh3)3 gave α-fluoroalkylated ketones.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Fluorine Chemistry - Volume 131, Issue 1, January 2010, Pages 86–90
Journal: Journal of Fluorine Chemistry - Volume 131, Issue 1, January 2010, Pages 86–90
نویسندگان
Kazuyuki Sato, Satoshi Yamazoe, Yukiko Akashi, Tetsuya Hamano, Arisa Miyamoto, Shuhei Sugiyama, Atsushi Tarui, Masaaki Omote, Itsumaro Kumadaki, Akira Ando,