کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1314545 | 975973 | 2010 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Hafnium (IV) bis(perfluorooctanesulfonyl)imide complex catalyzed synthesis of polyhydroquinoline derivatives via unsymmetrical Hantzsch reaction in fluorous medium Hafnium (IV) bis(perfluorooctanesulfonyl)imide complex catalyzed synthesis of polyhydroquinoline derivatives via unsymmetrical Hantzsch reaction in fluorous medium](/preview/png/1314545.png)
A facile and efficient synthesis of polyhydroquinoline derivatives was reported via four-component condensation reaction of aldehydes, dimedone, active methylene compounds, and ammonium acetate in the presence of Hf(NPf2)4 in C10F18 at 60 °C. The method offers several advantages including high yields, short reaction time, simple work-up procedure and catalyst reusability.
The synthesis of polyhydroquinoline derivatives via a four-component coupling reaction of aldehydes, dimedone, active methylene compounds, and ammonium acetate was successfully accomplished using metal bis(perfluorooctanesulfonyl)imide (M(NPf2)n, M = Sn, Hf, Yb, Sc, Y, Sm, La, Nd) as catalysts in fluorous solvent. Hafnium bis(perfluorooctanesulfonyl)imide catalyzed the high efficient preparation of polyhydroquinolines in fluorous solvent. Fluorous phase containing only catalyst can be reused several times.Figure optionsDownload as PowerPoint slide
Journal: Journal of Fluorine Chemistry - Volume 131, Issue 1, January 2010, Pages 111–114