Lipophilic thioguanosine: An anion receptor for cesium fluoride

► Lipophilic thioguanosine (TG) behaves as an anion receptor or sensor for CsF. ► TG could response CsF in water-organic mixed solvents such as D2O/CD3CN. ► Both deprotonation reaction and noncovalent interactions existed between TG and CsF. ► It is of interest for the interactions of TG with inorganic fluoride sources. ► This work may deal with the topic of the interactions of anions with DNA and RNA.