کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1314834 | 975988 | 2008 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Gem-difluorination in superacid: The dramatic role of halonium ions Gem-difluorination in superacid: The dramatic role of halonium ions](/preview/png/1314834.png)
In HF/SbF5, in the presence of CCl4 or NBS, unsaturated or hydroxylated piperidines yield difluoroanalogues in good yields. The ability to perform hydride abstraction on chloroderivatives, and the ability to form bridged bromonium ions from unsaturated substrates seem to completely influence the reaction course. Some aspects of the mechanism were clarified by DFT calculations.
In HF/SbF5, in the presence of CCl4 or NBS, unsaturated or hydroxylated piperidines yield difluoroanalogues in good yields. The ability to perform hydride abstraction on chloroderivatives, and the ability to form bridged bromonium ions from unsaturated substrates seem to completely influence the reaction course. Some aspects of the mechanism were clarified by DFT calculations.Figure optionsDownload as PowerPoint slide
Journal: Journal of Fluorine Chemistry - Volume 129, Issue 9, September 2008, Pages 775–780