کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1315117 | 976004 | 2010 | 5 صفحه PDF | دانلود رایگان |
The surfactant and antimicrobial activities of thiol and disulfide derivatives containing a quaternary ammonium group bearing variable perfluorinated carbon chains via an amide connector between the sulfur and nitrogen atoms were evaluated with the future aim to be grafted on metal surfaces for obtaining contact-active and non-adhesive auto-biocidal surfaces. Their biostatic and bactericidal activities against four microbial strains (Pseudomonas aeruginosa, Staphylococcus aureus, Aspergillus niger and Candida albicans) were measured. The presence of the thiol, disulfide and amide functions in these surfactants were discussed in relation with antimicrobial activity along with the influence of the length of fluorinated chains in order to determine which molecular parameters are ‘critical’ for biological activity.
The surface properties of mono- and bis-quaternary ammonium salts bearing perfluorinated chains with variable lengths were evaluated. Their antimicrobial activity versus Staphylococcus aureus, Pseudomonas aeruginosa, Aspergillus niger and Candida albicans was also studied.Figure optionsDownload as PowerPoint slide
Journal: Journal of Fluorine Chemistry - Volume 131, Issue 5, May 2010, Pages 592–596