Lithium bromide/triethylamine promoted tandem cycloaddition–oxidation reaction: A convenient access to 3-trifluoroacetyl pyrroles from N-alkylidene 2-amino esters and β-trifluoroacetyl vinyl ethyl ether

A convenient lithium bromide/triethylamine promoted tandem cycloaddition–oxidation reaction was developed to afford 3-trifluoroacetyl pyrroles in moderate to good yields from N-alkylidene 2-amino esters and β-trifluoroacetyl vinyl ethyl ether.

A convenient lithium bromide/triethylamine promoted tandem cycloaddition–oxidation reaction was developed to afford 3-trifluoroacetyl pyrroles in moderate to good yields from N-alkylidene 2-amino esters and β-trifluoroacetyl vinyl ethyl ether.Figure optionsDownload as PowerPoint slide