Sc[N(SO2C8F17)2]3 catalyzed condensation of β-naphthol and aldehydes in fluorous solvent: One-pot synthesis of 14-substituted-14H-dibenzo[a,j]xanthenes

A facile synthesis of 14-substituted-14H-dibenzo[a,j]xanthenes was proposed by one-pot condensation of β-naphthol with aryl or alkyl aldehydes by using Scandium bis(perfluorooctanesulfonyl)imide complex as catalyst and perfluorodecalin as sole solvent.

The synthesis of 14-substituted-14H-dibenzo[a,j]xanthenes through a condensation of β-naphthol with aldehydes was successfully accomplished using metal bis(perfluorooctanesulfonyl)imide (M(NPf2)n), M = Sn, Hf, Yb, Sc, Y, Sm, Eu, Td) as catalysts in fluorous solvent. Scandium bis(perfluorooctanesulfonyl)imide catalyzed the high efficient preparation of aryl or alkyl-14H-dibenzo[a,j]xanthenes in fluorous solvent. Fluorous phase containing only catalyst can be reused several times.Figure optionsDownload as PowerPoint slide