کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1315465 976033 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
One-pot synthesis of quinoline-4-carboxylic acid derivatives in water: Ytterbium perfluorooctanoate catalyzed Doebner reaction
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
One-pot synthesis of quinoline-4-carboxylic acid derivatives in water: Ytterbium perfluorooctanoate catalyzed Doebner reaction
چکیده انگلیسی

Ytterbium perfluorooctanoate [Yb(PFO)3] has been proved to be an efficient catalyst for Doebner reaction of pyruvic acid, aldehydes and amines under mild conditions in water to afford quinoline-4-caboxylic acid derivatives with three component one-pot method in good yields. The process is operationally simple and environmentally benign and the catalyst has readily been recycled for several times with consistent activity. Furthermore, a plausible mechanism for this transformation is also presented.

Ytterbium perfluorooctanoate [Yb(PFO)3] catalyzed efficient Doebner reaction through three component coupling reactions of pyruvic acid, amines and aldehydes in water was described as a novel procedure for the preparation of quinoline-4-carboxylic acid derivatives.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Fluorine Chemistry - Volume 130, Issue 4, April 2009, Pages 406–409
نویسندگان
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