Chemistry of difluorocarbene adducts: Stereospecific synthesis of conjugated fluoroolefins and 1,3-azabutadienes from gem-difluorocyclopropenyl ketones

Treatment of gem-difluorocyclopropenyl ketones with malonate anion, amine gave stereospecifically conjugated fluoroolefins and azabutadienes, respectively.

Ring opening reactions of gem-difluorocyclopropenyl ketones with malonate anion and amine were studied. Novel conjugated fluoroolefin and azabutadiene were stereospcifically synthesized from these reactions. Figure optionsDownload as PowerPoint slide