کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
13414315 | 1841235 | 2020 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Data on possible in vitro anti-diabetic effects of verticinone on β-TC6 pancreatic and C2C12 skeletal muscle cells
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Data on possible in vitro anti-diabetic effects of verticinone on β-TC6 pancreatic and C2C12 skeletal muscle cells Data on possible in vitro anti-diabetic effects of verticinone on β-TC6 pancreatic and C2C12 skeletal muscle cells](/preview/png/13414315.png)
چکیده انگلیسی
Verticinone as a steroidal alkaloid is one of the major active constituents of medicinal herb, Fritillaria imperialis with several pharmacological properties. Present data demonstrate an in vitro assessment of verticinone effects on β-TC6 pancreatic and C2C12 skeletal muscle cells include cell survival, activities of carbohydrate-hydrolyzing enzymes (α-amylase and α-glucosidase), levels of insulin secreted into the media, glucose uptake ability, advanced glycation end product (AGEs) include 3-deoxyglucosone, methylglyoxal, and pentosidine levels and the activity of glyoxalase I. Data reveals possible hypoglycemic potential of verticinone, although, the high concentrations of this compound were associated with elevated amount of AGEs and it should be assessed in future investigations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Data in Brief - Volume 28, February 2020, 104828
Journal: Data in Brief - Volume 28, February 2020, 104828
نویسندگان
Fargol Mashhadi Akbar Boojar, Reza Aghaei, Mahdi Mashhadi Akbar Boojar,