Kinetic resolution of C1-substituted oxabenzonorbornadienes by Ir-catalyzed asymmetric [2+2] cycloaddition reactions with arylacetylenes

The kinetic resolution of racemic C1-substituted oxabenzonorbornadienes was realized by iridium-catalyzed asymmetric [2+2] cycloaddition reaction with arylacetylenes. Cyclobutene products and unreacted C1-substituted oxabenzonorbornadienes were obtained with high to excellent enantiomeric purities.

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