کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1347275 980303 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Crystal structures of (2-substituted-5-N-tosyl)bicyclo[3.3.0]-5-azacyclooct-2-enone: a pseudo achiral crystal from enantiopure compound and a counter-example of Wallach’s rule
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Crystal structures of (2-substituted-5-N-tosyl)bicyclo[3.3.0]-5-azacyclooct-2-enone: a pseudo achiral crystal from enantiopure compound and a counter-example of Wallach’s rule
چکیده انگلیسی

An unusual crystallization affording an apparently pseudoachiral crystal from single enantiomers 1a and 1b was observed. In cases of enantiopure molecules such as 1a and 1b with structural flexibility, the tendency toward a centrosymmetric arrangement was so overwhelming that apparently achiral crystals were formed even by homochiral compounds via the formation of a pseudo-centrosymmetric asymmetric unit accompanying structural adjustment. In addition, these crystals of 1a constitute as a counter-example of Wallach’s rule.

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2,3,3a,4-Tetrahydro-6-phenyl-2-tosylcyclopenta[c]pyrrol-5-oneC20H19NO3SEe = 99%[α]D20=-87.0 (c 2.0, CH2Cl2)Source of chirality: chiral catalystAbsolute configuration: (3R)

2,3,3a,4-Tetrahydro-2-tosylcyclopenta[c]pyrrol-5-oneC14H15NO3SEe = 99%[α]D20=+193.7 (c 2.5, CH2Cl2)Source of chirality: chiral catalystAbsolute configuration: (3R)

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron: Asymmetry - Volume 20, Issue 15, 12 August 2009, Pages 1736–1741
نویسندگان
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