کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1348004 980334 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Direct asymmetric three-component Mannich reactions catalyzed by a siloxy serine organocatalyst in water
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Direct asymmetric three-component Mannich reactions catalyzed by a siloxy serine organocatalyst in water
چکیده انگلیسی

A siloxy-l-serine organocatalyst has been developed to catalyze the asymmetric three-component Mannich reactions in the presence of water via a biphasic system, furnishing the Mannich products in good yields and high enantioselectivities.

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(2S)-2-Benzyloxycarbonylamino-3-(tert-butyl-diphenyl-silanyloxy)-propionic acidC19H25NO3Si[α]D23=+2.6 (c 1.94, MeOH)Source of chirality: Z-Serine-OHAbsolute configuration: (S)

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron: Asymmetry - Volume 19, Issue 2, 6 February 2008, Pages 186–190
نویسندگان
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