Highly enantioselective hydrosilylation of simple ketones catalyzed by rhodium complexes of P-chiral diphosphine ligands bearing tert-butylmethylphosphino groups

P-Chiral diphosphine ligands, (S,S)-1,2-bis(tert-butylmethylphosphino)ethane [(S,S)-t-Bu-BisP∗], (R,R)-bis(tert-butylmethylphosphino)methane [(R,R)-t-Bu-MiniPHOS], and (R,R)-2,3-bis(tert-butylmethylphosphino)quinoxaline [(R,R)-QuinoxP∗], were applied to the rhodium-catalyzed enantioselective hydrosilylation of simple ketones. The corresponding secondary alcohols were obtained in high yields with good to excellent enantiomeric excesses of up to 99%.

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