کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1348546 | 980359 | 2006 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Simple and effective method for the deracemization of ethyl 1-hydroxyphosphinate using biocatalysts with lipolytic activity
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی معدنی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The kinetic resolution of ethyl (1-hydroxyethyl)phenylphosphinate was carried by enzymatic esterification with vinyl butyrate or by hydrolysis of ethyl (1-butyryloxyethyl)phenylphosphinate either by the use of lipases or whole cells of microorganisms (bacteria and fungi). Since no stereodifferentiation of the phosphinate moiety was observed, the biotransformations gave diastereoisomers of ethyl (1-hydroxyethyl)phenylphosphinate with excellent enantiomeric excesses above 98%, while the percentage conversion ranged from 10% to 49% depending upon the procedure and conditions of the biocatalysis.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron: Asymmetry - Volume 17, Issue 20, 6 November 2006, Pages 2870–2875
Journal: Tetrahedron: Asymmetry - Volume 17, Issue 20, 6 November 2006, Pages 2870–2875
نویسندگان
Paulina Majewska, Paweł Kafarski, Barbara Lejczak,