Chirality transfer in mandelate ionic liquids through ion pairing effects

Ion pairing in [N-(3′-oxohexyl)-N-methylimidazolium][(R)-mandelate] was probed as a function of its concentration in ethanol and compared to the corresponding [(S)-camphorsulfonate] ionic liquid. The applied methodologies comprised asymmetric hydrogenation with ee monitoring as well as independent diffusion-ordered NMR and conductivity measurements.

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