کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1349148 | 980385 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
High enantio- and diastereoselective induction of BINOL- and TADDOL-modified vinyloxy ethoxides in C-C coupling reactions with aldehydes
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی معدنی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
The basic reagent vinyloxyethoxy titanium trisisopropyloxide, easily modified by replacing two of the isopropyloxides with the optically active diol (R)- or (S)-BINOL, reacts with simple, prochiral aldehydes to give chiral β-hydroxy-1,3-dioxolanes with enantiomeric ratios up to 99:1. The same reagents, (R)- or (S)-configured, react with the chiral 2,3-O-isopropylidene-d-glyceraldehyde to give the corresponding open chain pentose derivatives. The main components have opposite descriptors at the newly created stereogenic center, indicating strong reagent control. A comparable system, modified by (R,R)- or (S,S)-TADDOL shows a weaker induction with the chiral aldehyde, but now with the same product configuration for both reagents, indicating predominant substrate control.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron: Asymmetry - Volume 16, Issue 23, 28 November 2005, Pages 3848-3852
Journal: Tetrahedron: Asymmetry - Volume 16, Issue 23, 28 November 2005, Pages 3848-3852
نویسندگان
Peter Maier, Hartmut Redlich, Jessica Richter,