A silver-lined anniversary of Fleet iminosugars: 1984–2009, from DIM to DRAM to LABNAc

The synthesis of iminosugars, polyhydroxylated N-heterocylces, has profoundly influenced the understanding of carbohydrate-processing and other enzyme systems. This review examines the prescient work over 25 years of one of the leading protagonists in the synthesis of these powerful compounds, examining strategy, detail and outcome.

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