Stereochemistry of nucleophilic ring-opening reactions of optically active N-acetyl-2-methoxycarbonylaziridine

The SN2-like mechanism of the nucleophilic attack of sodium azide on (S)-(−)-N-acetyl-2-methoxycarbonylaziridine was verified through the chemical correlation of the ring-opening products with (S)-(+)- or (R)-(−)-2,3-diaminopropanoic acid monohydrochloride.

The SN2-like mechanism of the nucleophilic attack of sodium azide on (S)-(−)-N-acetyl-2-methoxycarbonylaziridine was verified.Figure optionsDownload as PowerPoint slide