Diterpenoids from the South China Sea soft coral Sarcophyton solidum

• A new sarsolenane-type dierpene was obtained from the South China Sea soft coral Sarcophyton solidum.
• Seven known diterpenoids including two sarsolenanes, two capnosanes, and three cembranes were reported.
• Sarsolilide B (4) was firstly confirmed by single-crystal X-ray diffraction.
• Compounds 1, 3, 4, and 6–8 were isolated from S. solidum for the first time.

Chemical investigation of the South China Sea soft coral Sarcophyton solidum has led to the isolation of one new (1) and seven known (2–8) diterpenoids, including three sarsolenanes (1–3), two capnosanes (4 and 5), and three cembranes (6–8). Sarsolilide B (4) was firstly confirmed by single-crystal X-ray diffraction. Compounds 1, 3, 4, and 6–8 were isolated from S. solidum for the first time, and 1, 2, and 4–7 were considered as the chemotaxonomic markers for the species S. solidum.

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