A new triterpenoid and other constituents from Lepidogrammitis drymoglossoides

• Chemical constituents of a Lepidogrammitis drymoglossoides are studied.
• We report one new triterpenoid (1), two lignans (2, 3) and two glycosides (4, 5).
• Compounds 2–5 are isolated from the genus Lepidogrammitis for the first time.
• Compounds 1–3, 5 might serve as chemotaxonomic markers within Polypodiaceae.

Phytochemical investigation of a Chinese fern Lepidogrammitis drymoglossoides led to the isolation of five compounds, including one triterpenoid, two lignans and two glycosides. Their structures were determined to be filic-3-ene-28-oic acid (1), (−)-syringaresinol-4-O-beta-d-glucopyranoside (2), lyoniresinol (3), 4-O-beta-d-glucopyranosyl caffeic acid (4) and n-butyl-O-beta-d-fructopyranoside (5) on the basis of mass and NMR spectra and chemical and physical properties. Filic-3-ene-28-oic acid (1) is a new triterpenoid, while compounds 2–5 were isolated from the genus Lepidogrammitis for the first time. Chemotaxonomic significance of this investigation is summarized.