کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1393195 | 1501193 | 2010 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis, single-crystal characterization and preliminary biological evaluation of novel ferrocenyl pyrazolo[1,5-a]pyrazin-4(5H)-one derivatives
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis, single-crystal characterization and preliminary biological evaluation of novel ferrocenyl pyrazolo[1,5-a]pyrazin-4(5H)-one derivatives Synthesis, single-crystal characterization and preliminary biological evaluation of novel ferrocenyl pyrazolo[1,5-a]pyrazin-4(5H)-one derivatives](/preview/png/1393195.png)
چکیده انگلیسی
A series of novel ferrocenyl pyrazolo[1,5–a]pyrazin-4(5H)-one derivatives was synthesized and characterized by 1H NMR, 13C NMR, IR, HRMS and X-ray diffraction analysis. Preliminary evaluation of biological applications showed that the compounds 6c and 6f inhibit the growth of A549 cells in dosage-dependent manners through cell cycle arrest.
Novel ferrocenyl pyrazolo[1,5–a]pyrazin-4(5H)-one derivatives were synthesized and characterized by spectroscopy and X-ray diffraction analysis. The compounds 6c and 6f were found to inhibit the growth of A549 cells through cell cycle arrest.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 45, Issue 1, January 2010, Pages 210–218
Journal: European Journal of Medicinal Chemistry - Volume 45, Issue 1, January 2010, Pages 210–218
نویسندگان
Yong-Sheng Xie, Hong-Ling Zhao, Hua Su, Bao-Xiang Zhao, Jin-Ting Liu, Ji-Kun Li, Hong-Shui Lv, Bai-Shan Wang, Dong-Soo Shin, Jun-Ying Miao,