کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1393442 1501211 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Structure-activity relationships of sandalwood odorants: Total synthesis and fragrance properties of cyclopropano-β-santalol
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Structure-activity relationships of sandalwood odorants: Total synthesis and fragrance properties of cyclopropano-β-santalol
چکیده انگلیسی
The synthesis and odor properties of cyclopropano-β-santalol, a new santalol analogue, are described. The exocyclic double bond of the original molecule, β-santalol, is replaced by a cyclopropane ring. Despite the analogies in the binding properties between the double bond and cyclopropane this change in the bulky hydrophobic part of the molecule leads to the complete loss of the characteristic sandalwood odor: in an olfactory evaluation the (Z)-product appears spicy and sweet, the (E)-isomer woody, but neither of them exhibits the typical sandalwood character.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 43, Issue 7, July 2008, Pages 1525-1529
نویسندگان
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