Synthesis, antimycobacterial screening and ligand-based molecular docking studies on novel pyrrole derivatives bearing pyrazoline, isoxazole and phenyl thiourea moieties

Antitubercular activity of novel series of pyrrolyl chalcone, pyrazline, isoxazole and phenyl urea derivatives was analyzed. Molecular modeling constructed using Surflex-Dock study using enoyl ACP reductase from Mycobacterium tuberculosis.