کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1394452 | 1501158 | 2012 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of fluorescent ristocetin aglycon derivatives with remarkable antibacterial and antiviral activities
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis of fluorescent ristocetin aglycon derivatives with remarkable antibacterial and antiviral activities Synthesis of fluorescent ristocetin aglycon derivatives with remarkable antibacterial and antiviral activities](/preview/png/1394452.png)
چکیده انگلیسی
Isoindole and benzoisoindole derivatives of ristocetin aglycon have been prepared by reaction with o-phthalaldehyde or naphthalene-2,3-dialdehyde and various thiols. The new compounds exhibited potent antibacterial and anti-influenza virus activity. The cluster forming and fluorescent properties of the aglycon derivatives were also studied.
Figure optionsDownload as PowerPoint slideHighlights
► Synthesis of (benzo)isoindole-substituted aglycoristocetin derivatives.
► Antibacterial data showing remarkable efficacy against resistant strains.
► High antiviral activity against influenza A viruses.
► Characterization of the fluorescent properties of new derivatives.
► Demonstration of aggregation properties.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 58, December 2012, Pages 361–367
Journal: European Journal of Medicinal Chemistry - Volume 58, December 2012, Pages 361–367
نویسندگان
Attila Sipos, Gábor Máté, Erzsébet Rőth, Anikó Borbás, Gyula Batta, Ilona Bereczki, Sándor Kéki, István Jóna, Eszter Ostorházi, Ferenc Rozgonyi, Evelien Vanderlinden, Lieve Naesens, Pál Herczegh,