کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1395191 | 1501202 | 2009 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
2-Azetidinone derivatives: Design, synthesis and evaluation of cholesterol absorption inhibitors
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
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چکیده انگلیسی
Fourteen new derivatives of the 2-azetidinone cholesterol absorption inhibitors have been synthesized, and three of them were enantiomerically pure. All the new compounds were evaluated for their activity to inhibit cholesterol absorption in rats, and most of them showed comparable effects in lowering the levels of total cholesterol in the serum.
Fourteen new derivatives of the 2-azetidinone cholesterol absorption inhibitors have been synthesized. All the new compounds were evaluated for their activity to inhibit cholesterol absorption in rats.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 44, Issue 4, April 2009, Pages 1638–1643
Journal: European Journal of Medicinal Chemistry - Volume 44, Issue 4, April 2009, Pages 1638–1643
نویسندگان
Yubin Wang, Huibin Zhang, Wenlong Huang, Jing Kong, Jinpei Zhou, Beibei Zhang,