کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1395202 | 1501202 | 2009 | 6 صفحه PDF | دانلود رایگان |
A new series of complexes have been synthesized by template condensation of oxalyldihydrazide and benzil in methanolic medium in the presence of trivalent chromium, manganese and iron salts forming complexes of the type [M(C32H24N8O4)X]X2 where M = Cr(III), Mn(III), Fe(III) and X = Cl−1, NO3−1, CH3COO−1. The complexes have been characterized with the help of elemental analyses, conductance measurements, magnetic susceptibility measurements, electronic, NMR, infrared and far infrared spectral studies. On the basis of these studies, a five coordinate square pyramidal geometry has been proposed for all these complexes. The biological activities of the metal complexes have been tested in vitro against a number of pathogenic bacteria to assess their inhibiting potential. Some of these complexes have been found to exhibit remarkable antibacterial activities.
A new series of macrocyclic complexes have been synthesized by template method followed by their characterization using various physicochemical techniques. These complexes were also tested for their in vitro antibacterial acivity against some pathogenic bacteria. Some of these complexes have been found to exhibit potent antibacterial activity.Figure optionsDownload as PowerPoint slide
Journal: European Journal of Medicinal Chemistry - Volume 44, Issue 4, April 2009, Pages 1731–1736