کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1395458 | 1501221 | 2007 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and antibacterial activity of oxazolidinones containing triazolyl group
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
A new series of oxazolidinones containing triazolyl group has been synthesized and tested for in vitro antibacterial activity by MIC determination against a panel of resistant and susceptible Gram-positive organisms. Most of the analogs in this series displayed activity superior to linezolid and vancomycin in vitro. Further, in vivo efficacies of the selected oxazolidinones were also disclosed herein.
A new series of oxazolidinones containing triazolyl group has been synthesized and their in vitro antibacterial activity (MIC) was evaluated, furthermore, in vivo efficacies of the selected compounds were also disclosed herein.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 42, Issue 8, August 2007, Pages 1137–1143
Journal: European Journal of Medicinal Chemistry - Volume 42, Issue 8, August 2007, Pages 1137–1143
نویسندگان
Houxing Fan, Gang Xu, Yilang Chen, Zhiteng Jiang, Shuhua Zhang, Yushe Yang, Ruyun Ji,