کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1395458 1501221 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and antibacterial activity of oxazolidinones containing triazolyl group
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis and antibacterial activity of oxazolidinones containing triazolyl group
چکیده انگلیسی

A new series of oxazolidinones containing triazolyl group has been synthesized and tested for in vitro antibacterial activity by MIC determination against a panel of resistant and susceptible Gram-positive organisms. Most of the analogs in this series displayed activity superior to linezolid and vancomycin in vitro. Further, in vivo efficacies of the selected oxazolidinones were also disclosed herein.

A new series of oxazolidinones containing triazolyl group has been synthesized and their in vitro antibacterial activity (MIC) was evaluated, furthermore, in vivo efficacies of the selected compounds were also disclosed herein.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 42, Issue 8, August 2007, Pages 1137–1143
نویسندگان
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