کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1396444 | 1501187 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of some N-alkyl substituted urea derivatives as antibacterial and antifungal agents
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A series of N-alkyl substituted urea derivatives were synthesized and evaluated for their in vitro antibacterial and antifungal activities. The N-alkyl substituted urea derivatives bearing morpholine moiety (3a–3k) showed better activities than those bearing diethylamine moiety (2a–2f). Compounds having fluoro substituent at ortho (3c) and para (3b) positions of the phenyl ring exhibited potent antimicrobial activities against Gram-positive and Gram-negative bacteria as well as fungi.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 45, Issue 7, July 2010, Pages 3207–3212
Journal: European Journal of Medicinal Chemistry - Volume 45, Issue 7, July 2010, Pages 3207–3212
نویسندگان
Qing-Zhong Zheng, Kui Cheng, Xiao-Min Zhang, Kai Liu, Qing-Cai Jiao, Hai-Liang Zhu,