کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1397831 | 1501191 | 2010 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antioxidant and antiviral activities of silybin fatty acid conjugates
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Antioxidant and antiviral activities of silybin fatty acid conjugates Antioxidant and antiviral activities of silybin fatty acid conjugates](/preview/png/1397831.png)
چکیده انگلیسی
Two selective acylation methods for silybin esterification with long-chain fatty acids were developed, yielding a series of silybin 7-O- and 23-O-acyl-derivatives of varying acyl chain lengths. These compounds were tested for their antioxidant (inhibition of lipid peroxidation and DPPH-scavenging) and anti-influenza virus activities. The acyl chain length is an important prerequisite for both biological activities, as they improved with increasing length of the acyl moiety.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 45, Issue 3, March 2010, Pages 1059–1067
Journal: European Journal of Medicinal Chemistry - Volume 45, Issue 3, March 2010, Pages 1059–1067
نویسندگان
Radek Gažák, Kateřina Purchartová, Petr Marhol, Lucie Živná, Petr Sedmera, Kateřina Valentová, Nobuo Kato, Hiroyo Matsumura, Kunihiro Kaihatsu, Vladimír Křen,