Antimicrobial active macrocyclic complexes of Cr(III), Mn(III) and Fe(III) with their spectroscopic approach

A novel series of macrocyclic complexes of the type [M(C48H32N4)X]X2; where M = Cr(III), Fe(III) and Mn(III); X = Cl−, NO3−, CH3COO− have been synthesized by template condensation of 1,8-diaminonaphthalene and benzil in the presence of trivalent metal salts in methanolic medium. The complexes have been characterized with the help of elemental analyses, conductance measurements, magnetic measurements, electronic, NMR, infrared, far infrared and mass spectral studies. On the basis of these studies, a five coordinate square pyramidal geometry for all of these complexes has been proposed. These metal complexes were also tested for their in vitro antimicrobial activities to assess their inhibiting potential.

A novel series of macrocyclic complexes have been synthesized by template method followed by their characterization by various physicochemical techniques. These metal complexes were also tested for their in vitro antimicrobial activities against some bacterial and fungal strains to assess their inhibiting potential and the activities shown by these complexes were compared with standard drugs.Figure optionsDownload as PowerPoint slide