کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1399764 | 1501212 | 2008 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and antibacterial activity of bis-[2-hydroxy-3-(1,7,8,9,10-pentamethyl-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yloxy)-propyl]-dimethyl-ammonium chloride
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and antibacterial activity of bis-[2-hydroxy-3-(1,7,8,9,10-pentamethyl-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yloxy)-propyl]-dimethyl-ammonium chloride Synthesis and antibacterial activity of bis-[2-hydroxy-3-(1,7,8,9,10-pentamethyl-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yloxy)-propyl]-dimethyl-ammonium chloride](/preview/png/1399764.png)
چکیده انگلیسی
A new quaternary ammonium compound, bis-[2-hydroxy-3-(1,7,8,9,10-pentamethyl-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yloxy)-propyl]-dimethyl-ammonium chloride (4), was synthesized. The compound was investigated for antibacterial activity, including Gram-positive cocci and Gram-negative rods, and antifungal activity. Compound 4 showed significant inhibition against Staphylococcus aureus. Research was carried out over 4 standard strains and 40 hospital strains. Elementary analysis and/or MS, 1H NMR and 13C NMR spectra confirmed the identity of the products. The molecular structure of 3 was determined by an X-ray analysis.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 43, Issue 6, June 2008, Pages 1309–1314
Journal: European Journal of Medicinal Chemistry - Volume 43, Issue 6, June 2008, Pages 1309–1314
نویسندگان
Marta Struga, Jerzy Kossakowski, Joanna Stefańska, Andrzej Zimniak, Anna E. Koziol,