کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
144125 438922 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Porous magnetite secondary particles prepared by surfactant-free solvothermal method with non-contact heat-assisted drug releasing property
ترجمه فارسی عنوان
ذرات ثانویه مغناطیسی متخلخل تولید شده توسط روش حلالیته نشتی بدون سورفاکتانت با داروی آزاد شده از مواد گرمایی بدون تماس
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
چکیده انگلیسی


• Porous Fe3O4 secondary particles were prepared by surfactant-free solvothermal method.
• AC Magnetic Field (ACMF) was applied to Fe3O4 secondary particles and its temperature increased to 43.9 °C.
• Drug delivery ability was confirmed by investigating the release of ibuprofen.
• The drug release from ibuprofen-loaded Fe3O4 secondary particles was controlled by the applied ACMF.

Porous magnetite (Fe3O4) secondary particles were prepared by a surfactant-free solvothermal method of up to 4 h. Fe3O4 secondary particles prepared for 3 h were about 300 nm in average diameter, composed of aggregated primary particles, and had a porous structure. Potential application of the Fe3O4 secondary particles as a drug delivery agent was evaluated by estimating their release of property. The amount of ibuprofen released was increased when an alternating current magnetic field (ACMF, 120 kHz and 7.8 kA/m) was applied to the prepared magnetite clusters in phosphate buffered saline (PBS) solution. Moreover, as-prepared samples dispersed in water well and exhibited quick magnetic separation with the help of an external magnetic field from a magnet.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advanced Powder Technology - Volume 27, Issue 2, March 2016, Pages 513–520
نویسندگان
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