کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
158084 456994 2008 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Derivative-free optimal experimental design
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Derivative-free optimal experimental design
چکیده انگلیسی

We present a new derivative-free method for the calculation of a planned experiment's information content in optimal experimental design. We will prove that our new approach yields the same result as a calculation with the Fisher information matrix if the mathematical model is linear in the model parameters. The new algorithm is derived from a maximum a posteriori update and calculates the statistical moments of the experiment's trajectory employing the unscented transformation as a derivative-free procedure. For a demonstration of the applicability of the algorithm, we will focus on a biological system described by a simple, but very instructive biological growth model.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemical Engineering Science - Volume 63, Issue 19, October 2008, Pages 4873–4880
نویسندگان
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