The determination of volumetric standard states and solute–solute interactions in competitive quaternary aqueous solutions using a self-consistent multivariate approach

A general methodology involving semi-batch experimental design is proposed in order to determine the volumetric standard states as well as homotactic and heterotactic volumetric solute–solute interaction coefficients from the associated quaternary solutions alone. The densities of quaternary aqueous solutions consisting of three alcohol solutes, e.g. methanol, ethanol, and 1-propanol, in the range of concentrations 0.0000