کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
170400 458391 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Kinetic selection of polymeric guanosine architectures from dynamic supramolecular libraries
ترجمه فارسی عنوان
انتخاب سینتیکی معماری های گوانوزین پلیمری از کتابخانه های سوپرومولکولی دینامیکی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
چکیده انگلیسی

We report an original strategy to transcribe and to fix supramolecular guanosine architectures in self-organized polymers. In the first resolution step, the G-quartet and G-quadruplex architectures are pre-amplified in solution in the presence of K+ cations from a dynamic pool of ribbon-type or cyclic supramolecular architectures. Then in a second selection polymerization step, the G-quadruplex is kinetically fixed in a covalent polymethacrylate network via an irreversible amplification step. Both supramolecular and polymeric components mutually (synergistically) adapt their spatial constitution during simultaneous (collective) formation of micrometric self-organized hybrid domains. This contributes to the high level of adaptability and correlativity of the self-organization of the supramolecular G-quadruplexes and of the polymeric systems. Biomimetic-type hybrid systems can be generated by using this strategy.

We report the constitutional resolution and selection of the dynamic supramolecular guanosine systems by using a kinetically irreversible polymerization process.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comptes Rendus Chimie - Volume 18, Issue 9, September 2015, Pages 960–965
نویسندگان
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