کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
174731 458898 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Data and programs in support of network analysis of genes and their association with diseases
ترجمه فارسی عنوان
داده ها و برنامه ها در حمایت از تجزیه و تحلیل شبکه ژن ها و ارتباط آنها با بیماری ها
کلمات کلیدی
ارتباط های بیماری ـ ژن؛ شبکه های ژن ـ ژن؛ شبکه های بیماری ـ بیماری
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
چکیده انگلیسی

The network-based approaches that were employed in order to depict the relationships between human genetic diseases and their associated genes are described. Towards this direction, monopartite disease-disease and gene-gene networks were constructed from bipartite gene-disease association networks. The latter were created by collecting and integrating data from three diverse resources, each one with different content, covering from rare monogenic disorders to common complex diseases. Moreover, topological and clustering graph analyses were performed. The methodology and the programs presented in this article are related to the research article entitled “Network analysis of genes and their association with diseases” [1].

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Data in Brief - Volume 8, September 2016, Pages 1036–1039
نویسندگان
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