کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
175335 | 458908 | 2016 | 9 صفحه PDF | دانلود رایگان |
• A new series of benzo[a]phenoxazinium chlorides was synthesised in moderate yields.
• They exhibit high fluorescence quantum yields in ethanol.
• The fluorochromophores displayed more photostability in biological media and membranes, than in aqueous solutions.
A new series of benzo[a]phenoxazinium chlorides possessing mono and disubstituted amines with 3-chloropropyl groups at the 9-position, isopropyl, cyclohexyl and phenyl groups as terminals at 5-postion was synthesised. Photophysical studies were performed in dry ethanol and aqueous solutions. The terminals at the 5-amino position were found to influence the acid-base equilibrium. The presence of hydroxyl functionality at 2-position was found to introduce an additional basic form that is the one in equilibrium with the cationic acid form in dry ethanol solutions. The photostability of these compounds in different media was also investigated and a high resistance to photobleaching in model biological membranes was observed. In proteins a moderate of 20% photobleaching occurs in 1 h 30 min, while in water more than 60% of the compound molecules are photodegraded during the same time interval.
A new series of benzo[a]phenoxazinium chlorides possessing mono- or disubstituted amines with 3-chloropropyl groups at the 9-position, isopropyl, cyclohexyl and phenyl groups as terminals at 5-postion was synthesised. Photophysical studies were performed in dry ethanol and aqueous solutions. The photostability of these compounds in different media was also investigated.Figure optionsDownload as PowerPoint slide
Journal: Dyes and Pigments - Volume 132, September 2016, Pages 204–212