کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
176313 | 458940 | 2014 | 8 صفحه PDF | دانلود رایگان |
• Two simple dyes based on aza-crown ether were synthesized.
• The crystal structure of dye 2 was studied.
• Linear and nonlinear optical properties of dyes 1–2 were investigated.
• The results revealed that the dyes 1–2 have much large δ2PA.
• TPFM imagings of two dyes in HepG2 cell line were demonstrated.
Two novel 6-phenyl-2,2′-bipyridine derivatives based on aza-crown ether groups were synthesized and characterized, one of which was characterized by single crystal X-ray diffraction determination. Their linear photophysical properties were systematically investigated in various solvents. The nonlinear photophysical properties were investigated by two-photon induced fluorescence method. Both dyes exhibited large two-photon absorption cross-section (δ2PA). The cytotoxicity of the dyes was evaluated in HepG2 cell line to assess the potential application for biomedical imaging. Two-photon fluorescence microscopy (TPFM) imaging of two dyes in HepG2 cell line was demonstrated, which indicated that introduction of the hydrophilic aza-crown ether facilitates biological compatibility of dyes.
Journal: Dyes and Pigments - Volume 100, January 2014, Pages 142–149