کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
177731 | 458998 | 2010 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: 2-Quinolone and coumarin polymethines for the detection of proteins using fluorescence 2-Quinolone and coumarin polymethines for the detection of proteins using fluorescence](/preview/png/177731.png)
A series of novel, polymethine chalcone dye – 2-quinolone derivatives and their boron difluoride complexes were synthesized. The spectral-luminescence properties of a series of 2-quinolones and their coumarin analogues were characterized in the presence of a denaturing agent (sodium dodecyl sulfate), native bovine serum albumin as well as a combination of serum albumin and sodium dodecyl sulfate. A study of the influence of the BF2-ether group on the sensitivity of the polymethine dyes to proteins revealed that three of the dyes, namely two hydroxyquinoline dyes containing a 4-diethylamino-2-hydroxyphenyl substituent and a coumarine dye that contained an indolenine substituent, displayed high emission and bright fluorescence (quantum yield ≤ 0.27) and thus offer promise for use in protein detection.
Journal: Dyes and Pigments - Volume 84, Issue 2, February 2010, Pages 159–164