کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
177801 459001 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Photophysical characterization of fluorescent oxazol-5-one derivatives in PVC and their application as biosensors in the detection of ACh and AChE inhibitor: Donepezil
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Photophysical characterization of fluorescent oxazol-5-one derivatives in PVC and their application as biosensors in the detection of ACh and AChE inhibitor: Donepezil
چکیده انگلیسی

Reversible biosensors based on 2-(3,5-dinitrophenyl)-4-[4-(1,4,7,10-tetraoxa-13-azacyclopentadecyl)benzylidene]-5-oxazolone (CPO-I), 2-(4-nitrophenyl)-4-[4-(1,4,7,10-tetraoxa-13-azacyclopentadecyl)benzylidene]-5-oxazolone (CPO-II) and 2-(4-tolyl)-4-[4-(1,4,7,10-tetraoxa-13-azacyclopentadecyl)benzylidene]-5-oxazolone (CPO-III) derivatives immobilized in a polyvinylchloride matrix, doped with acetylcholinesterase, have been developed. The biosensors were calibrated for acetylcholine as neurotransmitter and the potent, selective and reversible cholinesterase inhibitor, donepezil ((±)-2-[(1-benzyl-piperidine-4-yl)ethyl]-5,6-dimetoxyindan-1-one hydrochloride). The photophysical parameters of all derivatives were also examined in PVC in which medium, they exhibited excellent photostability.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Dyes and Pigments - Volume 76, Issue 3, 2008, Pages 792–798
نویسندگان
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