کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
178227 459026 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and Type I/Type II photosensitizing properties of a novel amphiphilic zinc phthalocyanine
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Synthesis and Type I/Type II photosensitizing properties of a novel amphiphilic zinc phthalocyanine
چکیده انگلیسی

A novel amphiphilic zinc phthalocyanine (ZnPcLTs) has been synthesized, which possesses good amphiphilicity, and low aggregation. The generation efficiency of singlet oxygen and other active oxygen species' trapping rate studies were studied by electron spin resonance (ESR) spectroscopy. The results indicated that the photosensitizer possessed a higher active oxygen species generation efficiency than that of hematoporphyrin. The results of photodamage experiments towards calf-thymus DNA indicated that ZnPcLTs is a promising photosensitizer candidate for photodynamic therapy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Dyes and Pigments - Volume 71, Issue 1, 2006, Pages 61–67
نویسندگان
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