pH-regulated ionic conductance in a nanopore

• Analytical model for ionic current/conductance in a nanopore are derived.
• Surface chemistry and presence of multiple ionic species are taken into account.
• Model is verified by experimental data of conductance in silica nanopores.
• Nanopore conductance is functions of the background salt concentration and pH.

Analytical expressions for the pH-regulated ionic current/conductance in a cylindrical nanopore are derived for taking into account practical effects of multiple ionic species, surface chemistry reactions, and electroosmotic flow. Our model is verified by the experimental data of the conductance in the silica nanopore available in the literature. The validated analytical models are applicable to investigate electrokinetic ion transport, and to design the next-generation nanopore-based devices.

Analytical model for ionic conductance in a pH-regulated nanopore is derived and validated.Figure optionsDownload as PowerPoint slide