A new strategy for eliminating interference from EC′ mechanism during analytical measurements based on plane-band-recessed microdisk array electrodes

• A three-electrode generator–collector device is fabricated.
• A strategy of combining the device with an inverted operating mode is described.
• Eliminating interference from EC′ mechanism is achieved.

A new type of three-electrode generator–collector sensor is described for the selective detection of any target analyte whose CV is chemically reversible in the presence of any interferent whose CV is chemically irreversible. The device consists of a layer of metallic material (Au in this work) poked by an array of cylindrical pores containing a ring-band electrode (Au in this work) placed in their middle and a disk electrode at their bottom (Au in this work). Operating the array of recessed disk electrodes to monitor the product of the stable analyte electronation while the top plane and the ring-band electrodes are poised at a potential located on the analyte and on the interferent waves allows suppressing entirely any contamination of the analyte concentration measurement by direct or indirect (EC′) involvement of the interferent. The efficiency of such devices was successfully demonstrated based on the detection of dopamine in the presence of ascorbic acid in PBS electrolyte.