The comparison of magnetic circuits used in magnetic hyperthermia

• Various magnetic circuits can produce an AC magnetic field of sufficient intensity.
• The design of rotating magnetic field generator is made.
• The heat dissipation and SAR parameter of water dispersion of SPIONs are shown.

The magnetic nanoparticle hyperthermia experiments require a precise system of magnetic field generation. In this article we present the design of three circuits that can generate an alternating magnetic field (the double-layer solenoid, Helmholtz coils, the inductor with C-shaped ferromagnetic core) and one system of rotating magnetic field. The theoretical calculations have been made to compare the magnetic field intensity distribution along the axis of the coils. Also the inhomogeneity of the magnetic field was determined. Similar calculations have been made for ferromagnetic core inductor. It was also shown the relationship between the intensity of magnetic field and the air gap width of ferrite core. Moreover, it was made a proposal of rotating magnetic field generator consisting of three pairs of phase-tuned inductors. In the experimental section we presented the results of calorimetric measurements performed on water dispersion of SPIONs.

The three circuits generating the alternating magnetic field (the double-layer solenoid, Helmholtz coils, the inductor with C-shaped ferromagnetic core) and one system of rotating magnetic field that can be used in the field of magnetic hyperthermia experiments.Figure optionsDownload as PowerPoint slide