کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1804140 | 1024644 | 2007 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Polyaspartate coated magnetite nanoparticles for biomedical applications
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
فیزیک ماده چگال
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
The use of magnetic nanoparticles (MNP) in biomedical applications is subject to specific conditions. Special demands such as non-toxic core material and a biocompatible shell are prerequisites. These are fulfilled with magnetite cores and amino acid shell material, which provide different functional groups for coupling biomolecules as presented here. In this study the biocompatibility was tested by using breast cancer cell lines and leukocytes from peripheral blood. Functionalization with antibodies and the binding experiments detected by magneto-optical relaxation measurements confirm the bonding capacity and demonstrate the application of the presented MNP in magnetic immunoassays or magnetic drug targeting.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Magnetism and Magnetic Materials - Volume 311, Issue 1, April 2007, Pages 1–5
Journal: Journal of Magnetism and Magnetic Materials - Volume 311, Issue 1, April 2007, Pages 1–5
نویسندگان
Konstanze Aurich, Manuela Schwalbe, Joachim H. Clement, Werner Weitschies, Norbert Buske,