کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1804182 | 1024644 | 2007 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Preparation and characterization of manganese ferrite-based magnetic liposomes for hyperthermia treatment of cancer Preparation and characterization of manganese ferrite-based magnetic liposomes for hyperthermia treatment of cancer](/preview/png/1804182.png)
Comparative evaluation of two different methods of magnetic liposomes preparation, namely thin film hydration (TFH) and double emulsion (DE) with different molar ratios of egg-phosphatidyl choline (egg-PC) and cholesterol using lauric acid coated manganese ferrite-based aqueous magnetic fluid, is reported. TFH was found to be a better method of encapsulation and TFH 2:1 (egg-PC: cholesterol) magnetic liposomes showed the highest encapsulation efficiency and comparable heating ability to that of magnetic fluids. Stealth TFH 2:1 magnetic liposomes containing DSPE-PEG2000 were three-fold more cytocompatible as compared to the magnetic fluid. Stealth TFH 2:1 manganese ferrite-based magnetic liposomes might be useful for hyperthermia treatment of cancer.
Journal: Journal of Magnetism and Magnetic Materials - Volume 311, Issue 1, April 2007, Pages 208–215