کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1804205 | 1024644 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Magnetic vectoring of magnetically responsive nanoparticles within the murine peritoneum
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
فیزیک ماده چگال
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Magnetic vectoring of magnetically responsive nanoparticles within the murine peritoneum Magnetic vectoring of magnetically responsive nanoparticles within the murine peritoneum](/preview/png/1804205.png)
چکیده انگلیسی
Magnetically responsive nanoparticles (MNPs) might be candidates for pro-drug formulations for intraperitoneal (i.p.) treatment of ovarian cancer. We conducted feasibility experiments in an i.p. human ovarian carcinoma xenograft model to determine whether MNPs can be effectively vectored within this environment. Our initial results based on magnetic resonance imaging (MRI) indicate that i.p.-injected â¼15Â nm magnetite-based MNPs can in fact migrate toward NdFeB magnets externally juxtaposed to the peritoneal cavity above the xenografts growing in the anterior abdominal wall. MNP localization to the tumor/peri-tumoral environment occurs. Further development of this MNP pro-drug strategy is underway.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Magnetism and Magnetic Materials - Volume 311, Issue 1, April 2007, Pages 330-335
Journal: Journal of Magnetism and Magnetic Materials - Volume 311, Issue 1, April 2007, Pages 330-335
نویسندگان
Jim Klostergaard, James Bankson, Edmond Auzenne, Don Gibson, William Yuill, Charles E. Seeney,