A new approach to glucose sensing at gold electrodes

An oxidative peak in the cathodic scan is observed in the cyclic voltammetry of glucose at gold electrodes, its peak current density being proportional to glucose concentration in a wide potential range. The application of this phenomenon in blood glucose sensing has been hindered by the presence of inhibitors: the most problematic are chlorides due to their high concentration and difficult separation from glucose. In the present paper we propose a solution to this problem involving a three electrode, four step pulsed electrochemical detection technique.