کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1855643 1529411 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Diagnostics in mycosis fungoides and Sezary syndrome
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک هسته ای و انرژی بالا
پیش نمایش صفحه اول مقاله
Diagnostics in mycosis fungoides and Sezary syndrome
چکیده انگلیسی

AimThe aim of this paper was to present diagnostic methods helping in the recognition of mycosis fungoides (MF) and Sezary syndrome (SS).BackgroundMycosis fungoides is the most common form of primary cutaneous T-cell lymphomas. It is characterized by a distinctive long-term course and malignant T-cell proliferation. MF diagnosis is not easy, mainly due to the atypical clinical presentation of the disease at an early stage.Materials and methodsLow specific changes, which can be observed at the histopathological examination. Initially, the skin lesions may resemble psoriasis, atopic dermatitis or chronic eczema. Patients are qualified according to the available, and generally accepted WHO-EORTC classification, based on a combination of clinical and histopathological markers. From a clinical point of view, it is also important to carry out the qualification according to the TNMB assessment, which allows to specify the stage of the disease, and is helpful in the monitoring of the course of disease and therapeutic effects.ResultsIn this paper we try to present currently available diagnostic methods.ConclusionDiagnosis of MF and SS still causes many problems due to less characteristic changes in the early stage of disease and requires wide interdisciplinary knowledge.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reports of Practical Oncology & Radiotherapy - Volume 19, Issue 2, March–April 2014, Pages 72–76
نویسندگان
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